The high-end Nikon Super CoolScan 8000 ED Film & Slide Scanner drivers we never developed past the early 2000’s and because of this there is no x64 processor support. Drivers will work on Windows XP, 2000 so a dedicated machine could be setup to handle if original function is desired. Windows 10 was the last version of Windows to have a x86 version, but we don't know if the drivers from 20 years ago are compatible. Other than that there are third party driver options out there that offer a driver compatible with this scanner.