As there are numerous types of Nook devices out there using different hardware it is important to distinguish the different models. Most of the Samsung based readers will show as a mass storage device in Windows, Mac or Windows the Nook device will ask if you want to allow the USB connect computer to access the files on the device. In most cases you are not going to have to download any extra drivers to do any of these tasks. In any case the Samsung based devices can use the drivers below if needed for recover and lower level features.
A valuable resource before you start installing any drivers is to check out Barnes and Nobles Nook support page here: https://help.barnesandnoble.com/hc/en-us/categories/4520922548379-B-N-NOOK-Support
Software updates for the Nook can be done when the device is connected to WiFi these over the air updates improved system stability and add features.